Endocrine Abstracts

Background: Total and completion thyroidectomy are commonly performed operations for the treatment of thyroid disease. Post-operative hypocalcaemia is a frequent complication of this surgery, and is associated with morbidity and prolonged length of stay (LOS).Methods: In January 2010 we introduced a protocol for the avoidance and management of post-operative of hypocalcaemia based on risk-stratification by post-operative PTH levels in patients undergoing...

Primary hyperparathyroidism (PHPT) affects approximately 0.3% of the UK population. The most frequent cause is solitary parathyroid adenoma, less commonly parathyroid hyperplasia, multiple adenomas, and parathyroid carcinoma. Cinacalcet is a calcimimetic which may be used in treatment of PHPT in certain circumstances. We report here a case of PHPT, treated by Cinacalcet, wherein apparently spontaneous necrosis of a parathyroid adenoma and resolution of hypercalcaemia occurred....

A 28-year old Lithuanian woman presented with a 6-week history of firm anterior neck swelling. There were no symptoms of local obstruction, invasion, or thyroid dysfunction, and no past medical history, medication use or relevant family history. On initial assessment, she was euthyroid, with a 6 cm hard mass replacing the right lobe of the thyroid, a 2 cm lymph node lateral to it, but no other lymphadenopathy. No cellular material could be obtained on initial clinical and ultr...

Parathyroid cysts (PCs) are rare lesions usually found during exploration of neck and mediastinal masses. Ten percent of PCs can be functional and release parathyroid hormones causing hypercalcemia. Most PCs are small but lesions greater than 1 cm can exert pressure effects on adjacent structures\. Diagnosis can be challenging as PCs can mimic thyroid masses with no focal tracer uptake during most functional imaging modalities. Fine needle aspiration (FNA) can help if coupled ...